Binary interactome mapping to study human disease

by

Pascal Braun
Center for Cancer Systems Biology
Dana Farber Cancer Institute
Harvard University

Thursday, April 16, 2009
3:30 p.m.
402 Walter Library

We are systematically mapping the human binary interactome with the goal of generating and analyzing high throughput yeast two-hybrid interactions with high quality and high sensitivity for all pair wise combinations of predicted gene products for which we have at least one Gateway-cloned ORF available (Human ORFeome website, http://horfdb.dfci.harvard.edu/). I will discuss how this information can be used to study human disease.

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