Protein folding physics and computational modeling

by

Ken A. Dill
Pharmaceutical Chemistry
University of California San Francisco

Friday, January 18, 2008
2:30 p.m.
402 Walter Library

Protein molecules are linear polymer chains that fold up into particular 3-dimensional native structures to perform the functions of the cell. We are interested in: (a) the folding code — how the 1-dimensional monomer sequence encodes the 3-dimensional fold, (b) the folding problem — how the protein searches and finds it's native structure so quickly, and (c) a folding algorithm — a computational strategy for predicting the native structure from the amino acid sequence.

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